Relationship of the Tufts Quantitative Neuromuscular Exam (TQNE) and the Sickness Impact Profile (SIP) in measuring progression of ALS

D. McGuire, L. Garrison, C. Armon, R. Barohn, W. Bryan, R. Miller, G. Parry, J. Petajan, M. Ross

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

The Tufts Quantitative Neuromuscular Exam (TQNE) is a standardized tool for measuring muscle strength and pulmonary function in patients with amyotrophic lateral sclerosis (ALS). We describe the relationship of TQNE scores to functional disability and health-related quality of life as measured by the Sickness Impact Profile (SIP) in 524 ALS patients. There was a significant relationship (p < 0.0001) between TQNE and SIP scores, both in cross section and over time. TQNE scores strongly relate to ALS patients' quality of life and ability to perform activities of daily living.

Original languageEnglish (US)
Pages (from-to)1442-1444
Number of pages3
JournalNeurology
Volume46
Issue number5
StatePublished - May 1 1996

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