Relationship between smoking reduction and cessation among light smokers

Kola Okuyemi, Janet L Thomas, Jennifer Warren, Hongfei Guo, Jasjit S Ahluwalia

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Introduction: To determine the smoking reduction patterns of light smokers (≤10 CPD) and whether reduction predicts future cessation. Methods: Study is a secondary analysis of data that were derived from a 2 × 2 randomized study that assessed the efficacy of nicotine gum (vs. placebo) and counseling (motivational interviewing vs. health education) for smoking cessation among 755 light smokers. Participants were categorized into three groups based on self-reported CPD smoked at time of study enrollment compared with CPD smoked a year prior to enrollment. That is, (a) those who reduced number of cigarettes per day (CPD), (b) those who smoked the same number of CPD, and (c) those who increased their number of CPD. Sociodemographic and smoking characteristics were assessed at enrollment as well as cotinine-verified 7-day smoking abstinence rates at the Week 26 follow-up assessment. A stepwise logistic regression model to predict the probability abstinence at 26-week follow-up was also performed. Results: Compared with a year prior to enrollment, 43.7% of participants reduced, 35.2% smoked the same, and 21.2% increased their CPD. Compared with those who smoked the same or increased their CPD, those who had reduced their CPD were older, more likely to be males, smoked fewer CPD at enrollment, initiated smoking at a younger age, and less likely to be nicotine dependent. Adjusted logistic regression showed that those who had reduced their smoking prior to enrollment were more likely to quit at Week 26 (odds ratio [OR] = 1.77; 95% CI = 1.062-2.957; p = .029). Discussion: Findings suggest that reducing number of CPD smoked prior to enrolling in a clinical trial is a positive predictor of abstinence. Therefore, encouraging smoking reduction prior to attempting cessation may enhance cessation outcomes for light smokers.

Original languageEnglish (US)
Pages (from-to)1005-1010
Number of pages6
JournalNicotine and Tobacco Research
Issue number10
StatePublished - Sep 9 2010

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