Regulation of skeletal muscle glucose transport and glucose metabolism by exercise training

Parker L. Evans, Shawna L. McMillin, Luke A. Weyrauch, Carol A. Witczak

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations

Abstract

Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2 diabetes. However, there are critical differences between these two main forms of exercise training and the adaptations that they induce in the body that may account for their beneficial effects. This article reviews the literature and highlights key gaps in our current understanding of the effects of aerobic and resistance exercise training on the regulation of systemic glucose homeostasis, skeletal muscle glucose transport and skeletal muscle glucose metabolism.

Original languageEnglish (US)
Article number2432
JournalNutrients
Volume11
Issue number10
DOIs
StatePublished - Oct 2019
Externally publishedYes

Bibliographical note

Funding Information:
This research was funded by the National Institutes of Health (Grant#: R01DK103562; Grant#: F31DK119080) and the American College of Sports Medicine (Grant#: 18-00636). The APC was funded by the National Institutes of Health (Grant#: R01DK103562).

Publisher Copyright:
© 2019 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

  • Aerobic exercise
  • Blood glucose
  • Functional overload
  • GLUT
  • Hexokinase
  • Insulin resistance
  • Resistance exercise
  • SGLT
  • Type 2 diabetes
  • Weightlifting

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