Regulation of drug intake

Wendy J. Lynch, Marilyn E Carroll

Research output: Contribution to journalReview articlepeer-review

119 Scopus citations

Abstract

Regulation of drug intake refers to the maintenance of relatively constant levels of drug over a specified time period. An understanding of regulation of drug intake may be critical in determining how drugs function as reinforcers and how their reinforcing effects may be modified. However, little is known about regulation of drug intake, and the mechanisms underlying it are poorly understood. Three mechanisms that have proposed to account for findings of regulation of drug intake were discussed to determine their relevance for drug-reinforced responding. These mechanisms include aversive effects, direct effects, and satiation. Although a greater role for satiation was supported in this review, drugs may vary on the degree to which they can produce satiation and whether satiation acts in concert with either the aversive effects or the direct effects of drugs is unclear.

Original languageEnglish (US)
Pages (from-to)131-143
Number of pages13
JournalExperimental and Clinical Psychopharmacology
Volume9
Issue number2
DOIs
StatePublished - 2001

Fingerprint

Dive into the research topics of 'Regulation of drug intake'. Together they form a unique fingerprint.

Cite this