Regioselective solvent-phase deuteration of polyphenolic compounds informs their identification by mass spectrometry

Keyphrases

• Mass Spectrometry 100%
• Deuteration 100%
• Regioselectivity 100%
• Polyphenolic Compounds 100%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 66%
• MS-MS 66%
• Deuterium Labeling 66%
• Acid-catalyzed 66%
• Hydrogen-deuterium Exchange 66%
• Accurate Mass 66%
• Highly Sensitive 33%
• Aromatics 33%
• Proton 33%
• Complex Mixtures 33%
• Hydrolysis 33%
• Hydroxyl Group 33%
• Acid-labile 33%
• Glycosidic Linkage 33%
• Core Structure 33%
• Polyphenols 33%
• Methyl Groups 33%
• Structural Information 33%
• Red Wine 33%
• Tandem MS 33%
• Mass Spectral 33%
• MS Data 33%
• Glycosyl 33%
• Polyphenolics 33%
• Unknown Compound 33%
• Complementary Method 33%
• Spectral Measurement 33%
• Nucleophilic Aromatic Substitution 33%
• Tandem Mass 33%
• Complex Foods 33%
• Isomeric Forms 33%
• Compound Structure 33%
• Mass Data 33%
• Optimal Reaction Conditions 33%
• Isomerism 33%
• Structure Elucidation 33%
• Deuterium Exchange 33%
• Aromatic Core 33%
• Exchange Patterns 33%
• Compound Integrity 33%
• Metlin 33%

Chemistry

• Mass Spectrometry 100%
• Deuterium 100%
• Tandem Mass Spectrometry 40%
• Liquid Chromatography Mass Spectrometry (LCMS) 40%
• Hydrogen 40%
• Glycosidic Linkage 20%
• Hydroxyl 20%
• Methyl Group 20%
• Electrophilic Aromatic Substitution 20%
• Isomerism 20%
• Complex Mixture 20%
• Structure Elucidation 20%
• Spectroscopy 20%
• Polyphenol 20%
• Glycosyl Group 20%
• Enzymatic Hydrolysis 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Polyphenol Derivative 100%
• Deuterium 100%
• Structure Elucidation 20%
• Polyphenol 20%
• Methyl Group 20%
• Hydroxyl Group 20%