TY - JOUR
T1 - Reference ranges of PR duration and P-wave indices in individuals free of cardiovascular disease
T2 - The Multi-Ethnic Study of Atherosclerosis (MESA)
AU - Soliman, Elsayed Z.
AU - Alonso, Alvaro
AU - Misialek, Jeffrey R.
AU - Jain, Aditya
AU - Watson, Karol E.
AU - Lloyd-Jones, Donald M.
AU - Lima, Joao
AU - Shea, Steven
AU - Burke, Gregory L.
AU - Heckbert, Susan R.
N1 - Funding Information:
The MESA study was supported by contracts N01-HC-95159 through N01-HC-95169 from the National Heart, Lung and Blood Institute .
PY - 2013/11
Y1 - 2013/11
N2 - In this brief report, we provide normal reference ranges for PR duration [unadjusted and heart rate adjusted] and P-wave indices [duration, amplitude and terminal force in V1] in individuals free of cardiovascular disease and its risk factors. We used automatically processed digital ECG data from 1252 US participants [mean age 59 (± 10) years, 738 women, 588 whites, 207 African-Americans, 217 Hispanics, 240 Chinese] from the Multi-Ethnic Study of Atherosclerosis [MESA]. In multivariable adjusted linear regression models with PR and each P-wave variable as a separate outcome, significant age, sex and race differences in these markers were observed. Subsequently, we report reference ranges for abnormal [2nd and 98th percentiles], borderline abnormal [5th and 95th percentiles] and mean [SD] values of PR and P-wave indices stratified by age [middle age (45-64 years) and seniors (65-84 years)], sex [men and women] and race [whites, African Americans, Hispanics and Chinese].
AB - In this brief report, we provide normal reference ranges for PR duration [unadjusted and heart rate adjusted] and P-wave indices [duration, amplitude and terminal force in V1] in individuals free of cardiovascular disease and its risk factors. We used automatically processed digital ECG data from 1252 US participants [mean age 59 (± 10) years, 738 women, 588 whites, 207 African-Americans, 217 Hispanics, 240 Chinese] from the Multi-Ethnic Study of Atherosclerosis [MESA]. In multivariable adjusted linear regression models with PR and each P-wave variable as a separate outcome, significant age, sex and race differences in these markers were observed. Subsequently, we report reference ranges for abnormal [2nd and 98th percentiles], borderline abnormal [5th and 95th percentiles] and mean [SD] values of PR and P-wave indices stratified by age [middle age (45-64 years) and seniors (65-84 years)], sex [men and women] and race [whites, African Americans, Hispanics and Chinese].
KW - MESA
KW - P-wave indices
KW - PR interval
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U2 - 10.1016/j.jelectrocard.2013.05.006
DO - 10.1016/j.jelectrocard.2013.05.006
M3 - Article
C2 - 23806475
AN - SCOPUS:84886952264
SN - 0022-0736
VL - 46
SP - 702
EP - 706
JO - Journal of Electrocardiology
JF - Journal of Electrocardiology
IS - 6
ER -
