Reevaluation of the role of LIP-1 as an ERK/MPK-1 dual specificity phosphatase in the C. elegans germline

Keyphrases

• C. Elegans Germline 100%
• Extracellular Signal-regulated Kinase 100%
• DUSP1 100%
• MPK-1 100%
• Germ Cells 37%
• Phosphorylation 37%
• Molecular Targets 12%
• Signaling Pathway 12%
• Caenorhabditis Elegans 12%
• Gain-of-function mutation 12%
• Cellular Processes 12%
• Gain-of-function 12%
• Phenocopy 12%
• Active Sites 12%
• Orthologs 12%
• Dephosphorylation 12%
• Wide-ranging 12%
• Tissue Homeostasis 12%
• Activity in Vivo 12%
• Extracellular Signal-regulated Kinase Activation 12%
• Tight Regulation 12%
• Multisite Phosphorylation 12%
• Failure to Rescue 12%
• TEY Motif 12%
• Organismal Development 12%
• Genetic mutants 12%
• DUSP6 12%
• Fertility Defect 12%
• Overinterpretation 12%

Biochemistry, Genetics and Molecular Biology

• Germline 100%
• Dual-Specificity Phosphatase 100%
• Caenorhabditis Elegans 100%
• Extracellular Signal-Regulated Kinases 100%
• Germ Cell 100%
• Active Site 20%
• Genetics 20%
• Dephosphorylation 20%
• Phenocopy 20%
• DUSP6 20%
• Morphology 20%
• Homeostasis 20%
• Allele 20%
• Phosphotransferase 20%
• Kinase 20%