Reduced inhibition of endothelial-derived relaxing factor causes the hyperdynamic circulation in chronic severe anemia

I. S. Anand, Y. Chandrashekhar

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Patients with chronic severe anemia have a vasodilated state and hyperdynamic circulation. The cause of vasodilation in these patients is not known. We postulate that the low levels of hemoglobin in these patients results in reduced inhibition of basal EDRF activity leading to generalized vasodilation.

Original languageEnglish (US)
Pages (from-to)225-228
Number of pages4
JournalMedical Hypotheses
Volume41
Issue number3
DOIs
StatePublished - Sep 1993

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