Redox status and pulmonary vascular reactivity

E. K. Weir, J. W. Eaton, E. Chesler

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Oxygen radicals are produced during oxidative metabolism in proportion to the tissue oxygen tension. The studies reported here have shown that oxygen radicals or the sulfhydryl oxidant, diamide, caused pulmonary vasodilatation in the isolated perfused rat lung. Could oxygen radicals play a role in the physiologic control of pulmonary vascular smooth muscle tone?

Original languageEnglish (US)
Pages (from-to)249S-252S
JournalCHEST
Volume88
Issue number4 SUPPL.
DOIs
StatePublished - 1985

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