Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms

Yanli Ding; Jean Francis; Jeffrey Kalish; Anita Deshpande; Karen Quillen

doi:10.1093/ckj/sfw011

Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms

Yanli Ding, Jean Francis, Jeffrey Kalish, Anita Deshpande, Karen Quillen

Research output: Contribution to journal › Article › peer-review

Abstract

Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.

Original language	English (US)
Pages (from-to)	408-410
Number of pages	3
Journal	Clinical Kidney Journal
Volume	9
Issue number	3
DOIs	https://doi.org/10.1093/ckj/sfw011
State	Published - Jun 2016
Externally published	Yes

Bibliographical note

Publisher Copyright:
© The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA.

Keywords

Arteriovenous fistula
FSGS
Kidney transplantation
Plasmapheresis
Vascular access

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/ckj/sfw011

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title = "Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms",

abstract = "Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.",

keywords = "Arteriovenous fistula, FSGS, Kidney transplantation, Plasmapheresis, Vascular access",

author = "Yanli Ding and Jean Francis and Jeffrey Kalish and Anita Deshpande and Karen Quillen",

note = "Publisher Copyright: {\textcopyright} The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA.",

year = "2016",

month = jun,

doi = "10.1093/ckj/sfw011",

language = "English (US)",

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pages = "408--410",

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T1 - Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms

AU - Ding, Yanli

AU - Francis, Jean

AU - Kalish, Jeffrey

AU - Deshpande, Anita

AU - Quillen, Karen

N1 - Publisher Copyright: © The Author 2016. Published by Oxford University Press on behalf of ERA-EDTA.

PY - 2016/6

Y1 - 2016/6

N2 - Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.

AB - Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.

KW - Arteriovenous fistula

KW - FSGS

KW - Kidney transplantation

KW - Plasmapheresis

KW - Vascular access

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DO - 10.1093/ckj/sfw011

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Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms

Abstract

Bibliographical note

Keywords

UN SDGs

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