Recurrent Ameloblastoma of the Mandible With Unusual Granular Cell Component

Prokopios P. Argyris, Mackensie J.T. McBeain, Angela Rake, Stefan E. Pambuccian, Rajaram Gopalakrishnan, Ioannis G. Koutlas

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Ameloblastomas can present in various clinical and histomorphologic patterns. The granular cell variant accounts for only 3.5% to 5% of ameloblastomas. The aim of this case report is to present an example of ameloblastoma with unusual granular cell component, affecting a 63-year-old woman, in which both the inner and peripheral layers of follicles composed exclusively by eosinophilic granular cells. Assessment of the immunohistochemical and histochemical profile of the lesion was performed and the challenges of such a diagnosis were also addressed.

Original languageEnglish (US)
Pages (from-to)298-304
Number of pages7
JournalInternational Journal of Surgical Pathology
Issue number4
StatePublished - Jun 3 2015

Bibliographical note

Publisher Copyright:
© The Author(s) 2015.


  • Granular cell ameloblastoma
  • Immunohistochemistry
  • Intraosseous salivary gland tumors
  • Lysosomes
  • Odontogenic neoplasm


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