Recruitment of participants in the Lung Health Study, I: Description of Methods

Deborah A. Durkin, Marcus O. Kjelsberg, A. Sonia Buist, John E. Connett, Gregory R. Owens

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


The recruitment experience is described for a large multicenter clinical trial, the Lung Health Study, which required the screening of more than 73,000 male and female smokers aged 35-60. This paper summarizes the plans, methods, and recruiting experience of the 10 participating clinical centers. Recruitment proposals were prepared by each clinical centers as part of the contract application process. Recruitment directors and staff were appointed whose primary responsibility was recruitment. Only one clinical center retained its original plan throughout; most clinical centers achieved their recruitment goals by supplementing their originally proposed strategies with one or more methods. The most frequently used methods were worksite, public site, mass mail, telephone, media, and referral strategies. The most significant contributions to the success of the recruitment process were the willingness and initiative of the clinical centers' staff to explore alternative techniques that would take advantage of local circumstances and their ability to incorporate as many workable recruitment methods as necessary to achieve the goal.

Original languageEnglish (US)
Pages (from-to)20-37
Number of pages18
JournalControlled clinical trials
Issue number2 SUPPL.
StatePublished - Apr 1993

Bibliographical note

Funding Information:
Supported by funding from the Division of Lung Diseases of the National Heart, Lung and Blood Institute.


  • Recruitment
  • chronic obstructive pulmonary disease
  • clinical trials


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