Objectives: Autoimmune pancreatitis (AIP) represents a complex immune-mediated pancreas disorder. Pediatric AIP (P-AIP) is rare. We have recently summarized the characteristic features of P-AIP. We now aim to develop recommendation statements to standardize the diagnostic and therapeutic approach to P-AIP and facilitate future research in the field. Methods: A panel of pediatric gastroenterologists participating in the International Study Group of Pediatric Pancreatitis: In search for a cuRE was formedtodiscussandthenvoteon15recommendationstatements.Aconsensusof atleast80%wasobtainedfollowing3votingroundsandrevisionofthestatements. Results: We have now generated 15 statements to help standardize the approach to diagnosis and management of P-AIP. Conclusions: The first P-AIP recommendation statements developed by the International Study Group of Pediatric Pancreatitis: In search for a cuRE group are intended to bring standardization to the diagnosis and treatment of this rare childhood disorder. These statements may help guide a uniform approach to patient care and facilitate future research studies.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of pediatric gastroenterology and nutrition|
|State||Published - 2018|
Bibliographical noteFunding Information:
This work was supported by NIH DK096327 (A.U.), DK108334 (A.U,); by National Pancreas Foundation (A.U.); INSPPIRE registry was developed by CTSA (2UL1 TR000442) and REDCap.
M.L. is consultant for AbbVie, Inc; Nordmark Arzneimittel GmbH & Co. KG; is in the Board of Directors of the National Pancreas Association; receives royalties from Millipore Inc. I.S. is supported by a Restracomp Grant and a Fondation St Luc Grant. T.G. received a research grant from Vertex Pharmaceuticals. A.U. is a member of the American Board of Pediatrics, Subboard of Pediatric Gastroenterology. The other authors report no conflicts of interest.
- Autoimmune pancreatitis
- Idiopathic duct–centric pancreatitis
- Lymphoplasmacytic sclerosing pancreatitis