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The field of veterinary biologics has been the primary benefactor of the limited number of genetically engineered products. Several recombinant DNA (r-DNA) vaccines used to prevent enterotoxigenic Escherichia coli disease in livestock animals are currently available world-wide (e. g. , EcoBac, and Scourguard) and a vaccine for foot and mouth disease is available in limited markets. In this paper, the author discusses the rationale behind the development of r-DNA vaccines and some of the methods used in their preparation. Discussion of viral-based vaccines is minimal, although not excluded. The details of the processes used to develop an E. coli r-DNA vaccine are used as a primary example.

Original languageEnglish (US)
Title of host publicationBiotechnol, Appl and Res
PublisherTechnomic Publ Co
Number of pages8
ISBN (Print)0877623910
StatePublished - 1985


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