TY - JOUR
T1 - Recognition of patterned molecular ink with phage displayed peptides
AU - Cui, Yue
AU - Pattabiraman, Anupama
AU - Lisko, Bozhena
AU - Collins, Samantha C.
AU - McAlpine, Michael C.
PY - 2010/2/3
Y1 - 2010/2/3
N2 - (Figure Presented) The development of a reliable method for patterning and recognizing molecular inks could enable exciting avenues in fundamental research and novel applications. Phage display is a powerful method for identifying peptides that possess enhanced selectivity and binding affinity toward a variety of targets. Here, we demonstrate for the first time the immobilization and recognition of a small molecular ink with screened phage displayed peptides. Our approach is based on a unique mix of comprehensive phage displayed peptide screening processes, along with novel micropatterning techniques. These results, combined with the large variety of available inks and surface chemistries, could open up opportunities in cell biology, nanomaterials self-assembly, selective sensors, and even energy storage applications.
AB - (Figure Presented) The development of a reliable method for patterning and recognizing molecular inks could enable exciting avenues in fundamental research and novel applications. Phage display is a powerful method for identifying peptides that possess enhanced selectivity and binding affinity toward a variety of targets. Here, we demonstrate for the first time the immobilization and recognition of a small molecular ink with screened phage displayed peptides. Our approach is based on a unique mix of comprehensive phage displayed peptide screening processes, along with novel micropatterning techniques. These results, combined with the large variety of available inks and surface chemistries, could open up opportunities in cell biology, nanomaterials self-assembly, selective sensors, and even energy storage applications.
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U2 - 10.1021/ja9081809
DO - 10.1021/ja9081809
M3 - Article
C2 - 20052979
AN - SCOPUS:77950449050
SN - 0002-7863
VL - 132
SP - 1204
EP - 1205
JO - Journal of the American Chemical Society
JF - Journal of the American Chemical Society
IS - 4
ER -