Receptor sensitivity: When T cells lose their sense of self

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

The T-cell antigen receptor binds to self-MHC molecules with low affinity. Recent reports disagree as to whether this interaction sensitizes or desensitizes the receptor. Here we discuss how these findings might be reconciled.

Original languageEnglish (US)
Pages (from-to)R239-R241
JournalCurrent Biology
Volume13
Issue number6
DOIs
StatePublished - Mar 18 2003

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