Recent advances in retrovirus vector technology

Kathleen A. Boris-Lawrie, Howard M. Temin

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

Retroviral vectors are widely used for the study of retroviral replication and to introduce DNA into somatic cells. An exciting new approach in retroviral vector technology is the use of internal ribosome entry sites from picornaviruses to provide stable expression of multiple genes. In addition, strategies are being developed that target the expression of retroviral vectors to specific cell populations.

Original languageEnglish (US)
Pages (from-to)102-109
Number of pages8
JournalCurrent Opinion in Genetics and Development
Volume3
Issue number1
DOIs
StatePublished - Feb 1993

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