Recent advances in retrovirus vector technology

Kathleen A. Boris-Lawrie; Howard M. Temin

doi:10.1016/S0959-437X(05)80349-1

Recent advances in retrovirus vector technology

Kathleen A. Boris-Lawrie, Howard M. Temin

Host-Pathogen Interface Biology

Research output: Contribution to journal › Article › peer-review

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Abstract

Retroviral vectors are widely used for the study of retroviral replication and to introduce DNA into somatic cells. An exciting new approach in retroviral vector technology is the use of internal ribosome entry sites from picornaviruses to provide stable expression of multiple genes. In addition, strategies are being developed that target the expression of retroviral vectors to specific cell populations.

Original language	English (US)
Pages (from-to)	102-109
Number of pages	8
Journal	Current Opinion in Genetics and Development
Volume	3
Issue number	1
DOIs	https://doi.org/10.1016/S0959-437X(05)80349-1
State	Published - Feb 1993

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title = "Recent advances in retrovirus vector technology",

abstract = "Retroviral vectors are widely used for the study of retroviral replication and to introduce DNA into somatic cells. An exciting new approach in retroviral vector technology is the use of internal ribosome entry sites from picornaviruses to provide stable expression of multiple genes. In addition, strategies are being developed that target the expression of retroviral vectors to specific cell populations.",

author = "Boris-Lawrie, {Kathleen A.} and Temin, {Howard M.}",

year = "1993",

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AU - Temin, Howard M.

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AB - Retroviral vectors are widely used for the study of retroviral replication and to introduce DNA into somatic cells. An exciting new approach in retroviral vector technology is the use of internal ribosome entry sites from picornaviruses to provide stable expression of multiple genes. In addition, strategies are being developed that target the expression of retroviral vectors to specific cell populations.

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Recent advances in retrovirus vector technology

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