Retroviral vectors are widely used for the study of retroviral replication and to introduce DNA into somatic cells. An exciting new approach in retroviral vector technology is the use of internal ribosome entry sites from picornaviruses to provide stable expression of multiple genes. In addition, strategies are being developed that target the expression of retroviral vectors to specific cell populations.
|Original language||English (US)|
|Number of pages||8|
|Journal||Current Opinion in Genetics and Development|
|State||Published - Feb 1993|