Recent advances in active compression-decompression cardiopulmonary resuscitation

Pamela Sukhum, Wolfgang Voelckel, Keith G. Lurie

Research output: Contribution to journalArticlepeer-review


In an attempt to improve upon the currently poor outcomes for patients in cardiac arrest, new methods and devices have been developed to enhance the efficiency and efficacy of standard cardiopulmonary resuscitation (CPR). One new approach, active compression-decompression (ACD) CPR was developed to lower the intrathoracic pressure during the decompression phase of CPR, thereby enhancing venous blood return to the thorax. Over the past decade the ACD CPR device has been extensively evaluated in animals and humans. ACD CPR is the only new approach for improving CPR efficacy with a mechanical device that has achieved clinical relevance. More recently, an inspiratory impedance threshold valve (ITV(TM)) has been developed that causes a further reduction in intrathoracic pressures, augmenting the efficiency of both standard and ACD CPR. Consequently, ACD CPR and the impendance valve were recently recommended by the American Heart Association. Clinical trials are underway to determine the long-term, potential value of these new technologies.

Original languageEnglish (US)
Pages (from-to)483-496
Number of pages14
JournalBailliere's Best Practice and Research in Clinical Anaesthesiology
Issue number3
StatePublished - 2000


  • Active compression-decompression
  • CPR
  • CPR devices
  • CPR techniques
  • Cardiac arrest
  • Cardiopulmonary resuscitation
  • ITV
  • Inspiratory impedance valve
  • Ventricular fibrillation

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