Reassembly of a spherical virus in mild conditions

K. W. Adolph; P. J.G. Butler

doi:10.1038/255737a0

Reassembly of a spherical virus in mild conditions

K. W. Adolph
, P. J.G. Butler

Biochemistry, Molecular Biology, and Biophysics (TMED)

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

ALTHOUGH successful reassembly of a number of spherical viruses has been reported^1-5, this has hitherto only been accomplished in conditions which are clearly non-physiological. We now report the reassembly of cowpea chlorotic mottle virus (CCMV) in mild conditions, ∼pH 6, ionic strength 0.1 or 0.2 and 20 to 25 °C; conditions which are plausible for an in vivo assembly reaction.

Original language	English (US)
Pages (from-to)	737-738
Number of pages	2
Journal	Nature
Volume	255
Issue number	5511
DOIs	https://doi.org/10.1038/255737a0
State	Published - 1975

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Copyright 2007 Elsevier B.V., All rights reserved.

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title = "Reassembly of a spherical virus in mild conditions",

abstract = "ALTHOUGH successful reassembly of a number of spherical viruses has been reported1-5, this has hitherto only been accomplished in conditions which are clearly non-physiological. We now report the reassembly of cowpea chlorotic mottle virus (CCMV) in mild conditions, ∼pH 6, ionic strength 0.1 or 0.2 and 20 to 25 °C; conditions which are plausible for an in vivo assembly reaction.",

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T1 - Reassembly of a spherical virus in mild conditions

AU - Adolph, K. W.

AU - Butler, P. J.G.

PY - 1975

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N2 - ALTHOUGH successful reassembly of a number of spherical viruses has been reported1-5, this has hitherto only been accomplished in conditions which are clearly non-physiological. We now report the reassembly of cowpea chlorotic mottle virus (CCMV) in mild conditions, ∼pH 6, ionic strength 0.1 or 0.2 and 20 to 25 °C; conditions which are plausible for an in vivo assembly reaction.

AB - ALTHOUGH successful reassembly of a number of spherical viruses has been reported1-5, this has hitherto only been accomplished in conditions which are clearly non-physiological. We now report the reassembly of cowpea chlorotic mottle virus (CCMV) in mild conditions, ∼pH 6, ionic strength 0.1 or 0.2 and 20 to 25 °C; conditions which are plausible for an in vivo assembly reaction.

UR - https://www.scopus.com/pages/publications/0016862432

UR - https://www.scopus.com/pages/publications/0016862432#tab=citedBy

U2 - 10.1038/255737a0

DO - 10.1038/255737a0

M3 - Article

C2 - 1134572

AN - SCOPUS:0016862432

SN - 0028-0836

VL - 255

SP - 737

EP - 738

JO - Nature

JF - Nature

IS - 5511

ER -

Reassembly of a spherical virus in mild conditions

Abstract

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