Abstract
The mechanism by which copper complexes bind and activate dioxygen was analyzed. The kinetic and thermodynamic information was obtained through cryogenic stopped-flow studies of the oxygenation of Cu(I) compounds. It was shown that protonation or acylation of peroxo copper species appears to enhance their O-atom transfer reactivity. It was concluded that O-O homolysis or heterolysis in CuOOH(R) complexes is energetically disfavored because of thermodynamic instability of the resulting Cu(III/IV)-oxo species.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1047-1076 |
| Number of pages | 30 |
| Journal | Chemical Reviews |
| Volume | 104 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2004 |