Reactivation of Porcine Cytomegalovirus through Allogeneic Stimulation

Maria Isabel M.C. Guedes, Jack M. Risdahl, Barry Wiseman, Thomas W. Molitor

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Reactivation of latent porcine cytomegalovirus after coculture of peripheral blood mononuclear cells (PB-MCs) from pigs with different genetic backgrounds was investigated. Nine of 10 allogeneic coculture pairs were PCR (DNA) positive, whereas 7 coculture pairs had porcine cytomegalovirus (PCMV) RNA, an indication of virus replication. The cell subpopulations harboring PCMV were monocytes and CD8+ T cells.

Original languageEnglish (US)
Pages (from-to)1756-1758
Number of pages3
JournalJournal of clinical microbiology
Volume42
Issue number4
DOIs
StatePublished - Apr 2004

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