(Figure Presented) The concentration of reactive metal hydride (Met-H) reducing agents can be determined (in ≤20 min) using No-D NMR spectroscopy. The method involves (i) reacting Met-H with an excess of p-methoxybenzaldehyde, (ii) quenching with excess acetic acid, (iii) recording the No-D NMR spectrum of this homogeneous mixture, and (iv) deducing the concentration of Met-H from the % conversion (as measured by integration). By a conceptually related method, the titer of the basic alkali metal hydrides KH and NaH can also be determined.
|Original language||English (US)|
|Number of pages||4|
|State||Published - May 26 2005|