Abstract
The reaction of α-halosubstituted β-ethoxyvinyl trifluomethyl ketones with 2-aminopyridine gives 3-trifluoroacetyl imidazo [1,2-a]pyridine and 3-halo-1,1,1,-trifluoro-4-(2-pyridinylamino)-3-buten-2-ones. The product ratio depends on the nature of the α-halogen atom and the solvent.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 193-197 |
| Number of pages | 5 |
| Journal | Journal of Fluorine Chemistry |
| Volume | 117 |
| Issue number | 2 |
| DOIs | |
| State | Published - Oct 28 2002 |
Bibliographical note
Copyright:Copyright 2021 Elsevier B.V., All rights reserved.
Keywords
- Amination
- Bicyclic heterocyclic compounds
- Cyclization
- Enones
- Fluorinated α-enamino ketones
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