Abstract
At the present time monotherapy is preferable to polytherapy if the epilepsy can be controlled with a single drug. However, persons with intractable epilepsy may need more than one antiepileptic drug to attain the best seizure control with the fewest side-effects. Although clinical studies have not been performed to identify the best combinations, rational polytherapy would imply combining antiepileptic drugs with different mechanisms of action.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 749-755 |
| Number of pages | 7 |
| Journal | Bailliere's Clinical Neurology |
| Volume | 5 |
| Issue number | 4 |
| State | Published - 1996 |
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