Rational monotherapy for epilepsy

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3 Scopus citations


At the present time monotherapy is preferable to polytherapy if the epilepsy can be controlled with a single drug. However, persons with intractable epilepsy may need more than one antiepileptic drug to attain the best seizure control with the fewest side-effects. Although clinical studies have not been performed to identify the best combinations, rational polytherapy would imply combining antiepileptic drugs with different mechanisms of action.

Original languageEnglish (US)
Pages (from-to)749-755
Number of pages7
JournalBailliere's Clinical Neurology
Issue number4
StatePublished - 1996


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