Rational design of acid-labile branched polycation with superior gene transfection capacity

Keyphrases

• Acid-labile 100%
• Acidic pH 33%
• Amines 66%
• Amino Alcohols 100%
• Amino Group 33%
• Branched Polyethyleneimine 66%
• Cationic Polymer 33%
• Chain Branching 33%
• Chain Type 33%
• Degree of Branching 66%
• Design Principles 33%
• Effective Genes 33%
• Endosomal 33%
• Gene Carrier 66%
• Gene Therapy 33%
• Gene Transfection 100%
• Intermediate Degrees 33%
• Low Cytotoxicity 33%
• Multiple Design 33%
• New Series 33%
• Physiological Media 33%
• Plasmid DNA (pDNA) 33%
• Poly(ortho ester) 100%
• Polycation 100%
• Polymer Degradability 33%
• Polyplexes 33%
• Rapid Release 33%
• Rational Design 100%
• Rational Screening 33%
• Secondary Amines 33%
• Structure-activity Relationship 33%
• Tertiary Amine 33%
• Transfection Efficiency 33%

Biochemistry, Genetics and Molecular Biology

• Cytotoxicity 50%
• Gene Therapy 50%
• Plasmid 50%
• Polymerization 50%
• Structure Activity Relation 50%
• Transfection 100%

Material Science

• Design Principle 100%
• Gene Therapy 100%