Rational design and synthesis of novel nucleotide anti-Giardia agents

Dae Hwan Suk; Laurent Bonnac; Christine C. Dykstra; Krzysztof W. Pankiewicz; Steven E. Patterson

doi:10.1016/j.bmcl.2007.01.014

Rational design and synthesis of novel nucleotide anti-Giardia agents

Dae Hwan Suk
, Laurent Bonnac
, Christine C. Dykstra
, Krzysztof W. Pankiewicz
, Steven E. Patterson

Center for Drug Design

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

Original language	English (US)
Pages (from-to)	2064-2067
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	17
Issue number	7
DOIs	https://doi.org/10.1016/j.bmcl.2007.01.014
State	Published - Apr 1 2007

Keywords

Anti-Giardia drug
Cyst wall synthesis
Giardiasis
Nucleotide

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10.1016/j.bmcl.2007.01.014

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@article{bd1a7baa31344c65a5de3fd64661edbf,

title = "Rational design and synthesis of novel nucleotide anti-Giardia agents",

abstract = "Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.",

keywords = "Anti-Giardia drug, Cyst wall synthesis, Giardiasis, Nucleotide",

author = "Suk, \{Dae Hwan\} and Laurent Bonnac and Dykstra, \{Christine C.\} and Pankiewicz, \{Krzysztof W.\} and Patterson, \{Steven E.\}",

year = "2007",

month = apr,

day = "1",

doi = "10.1016/j.bmcl.2007.01.014",

language = "English (US)",

volume = "17",

pages = "2064--2067",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Ltd",

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TY - JOUR

T1 - Rational design and synthesis of novel nucleotide anti-Giardia agents

AU - Suk, Dae Hwan

AU - Bonnac, Laurent

AU - Dykstra, Christine C.

AU - Pankiewicz, Krzysztof W.

AU - Patterson, Steven E.

PY - 2007/4/1

Y1 - 2007/4/1

N2 - Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

AB - Design and synthesis of a novel nucleotide anti-Giardia agent that is micromolar inhibitor of Giardia trophozoite growth in culture is described.

KW - Anti-Giardia drug

KW - Cyst wall synthesis

KW - Giardiasis

KW - Nucleotide

UR - https://www.scopus.com/pages/publications/33847643327

UR - https://www.scopus.com/pages/publications/33847643327#tab=citedBy

U2 - 10.1016/j.bmcl.2007.01.014

DO - 10.1016/j.bmcl.2007.01.014

M3 - Article

C2 - 17258459

AN - SCOPUS:33847643327

SN - 0960-894X

VL - 17

SP - 2064

EP - 2067

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 7

ER -

Rational design and synthesis of novel nucleotide anti-Giardia agents

Abstract

Keywords

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