Rate of force production and relaxation is impaired in patients with focal hand dystonia

Janey Prodoehl, Colum D. MacKinnon, Cynthia L. Comella, Daniel M. Corcos

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

One factor, which may contribute to slowed movement in dystonia, is impairment in controlling the voluntary rate of motor output. This study examined the ability of patients with focal hand dystonia to rapidly turn force on and off at the wrist and elbow joints. Dystonic patients were slower than controls in rapidly turning on force from rest at both joints, passively relaxing force and rapidly reversing force output from a steady-state flexion contraction. Adding a preload did not improve the ability of dystonic subjects to rapidly turn on force. These results support the idea that dystonia is a disorder of impaired motor cortical activation, possibly due to basal ganglia dysfunction.

Original languageEnglish (US)
Pages (from-to)363-371
Number of pages9
JournalParkinsonism and Related Disorders
Volume12
Issue number6
DOIs
StatePublished - Sep 1 2006

Fingerprint

Aptitude
Dystonia
Wrist Joint
Elbow Joint
Basal Ganglia
Joints
Focal Task-Specific Dystonia
Motor Disorders

Keywords

  • Basal ganglia
  • Isometric
  • Motor control
  • Writer's cramp

Cite this

Rate of force production and relaxation is impaired in patients with focal hand dystonia. / Prodoehl, Janey; MacKinnon, Colum D.; Comella, Cynthia L.; Corcos, Daniel M.

In: Parkinsonism and Related Disorders, Vol. 12, No. 6, 01.09.2006, p. 363-371.

Research output: Contribution to journalArticle

Prodoehl, Janey ; MacKinnon, Colum D. ; Comella, Cynthia L. ; Corcos, Daniel M. / Rate of force production and relaxation is impaired in patients with focal hand dystonia. In: Parkinsonism and Related Disorders. 2006 ; Vol. 12, No. 6. pp. 363-371.
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