Rapid vacuolar sequestration: The horseweed glyphosate resistance mechanism

Xia Ge, D. André d'Avignon, Joseph J.H. Ackerman, R. Douglas Sammons

Research output: Contribution to journalArticlepeer-review

227 Scopus citations


Background: Glyphosate-resistant (GR) weed species are now found with increasing frequency and threaten the critically important GR weed management system. Results: The reported 31P NMR experiments on glyphosate-sensitive (S) and glyphosate-resistant (R) horseweed, Conyza canadensis (L.) Cronq., show significantly more accumulation of glyphosate within the R biotype vacuole. Conclusions: Selective sequestration of glyphosate into the vacuole confers the observed horseweed resistance to glyphosate. This observation represents the first clear evidence for the glyphosate resistance mechanism in C. canadensis.

Original languageEnglish (US)
Pages (from-to)345-348
Number of pages4
JournalPest management science
Issue number4
StatePublished - Apr 2010
Externally publishedYes


  • Conyza canadensis
  • Glyphosate
  • Glyphosate-resistant
  • In vivo P NMR


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