Rapid and Extensive Expansion in the United States of a New Multidrug-resistant Escherichia coli Clonal Group, Sequence Type 1193

Veronika L. Tchesnokova, Elena Rechkina, Lydia Larson, Kendra Ferrier, Jamie Lee Weaver, David W. Schroeder, Rosemary She, Susan M. Butler-Wu, Maria E. Aguero-Rosenfeld, Danielle Zerr, Ferric C. Fang, James Ralston, Kim Riddell, Delia Scholes, Scott Weissman, Kaveri Parker, Brad Spellberg, James R. Johnson, Evgeni V. Sokurenko

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone- sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates.

Original languageEnglish (US)
Pages (from-to)334-337
Number of pages4
JournalClinical Infectious Diseases
Volume68
Issue number2
DOIs
StatePublished - Jan 7 2019

Keywords

  • Escherichia coli
  • Fluoroquinolone resistance
  • Urinary tract infections

PubMed: MeSH publication types

  • Journal Article
  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

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