Vorzeitiger Abbruch randomisierter kontrollierter Studien: Vorteilsbedingter Therapieeffekt

Translated title of the contribution: Randomized controlled trials terminated prematurely: Beneficial therapy effects

L. A. Kluth, M. Rink, S. A. Ahyai, M. Fisch, S. F. Shariat, P. Dahm

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Randomized controlled trials (RCTs) stopped prematurely for beneficial therapy effects are becoming increasingly more prevalent in the urological literature and often receive great attention in the public and medical media. Urologists who practice evidence-based medicine should be aware of the potential bias and the different reasons why and how early termination of RCTs can and will affect the results. This review provides insights into the challenges clinical urologists face by interpreting the results of prematurely terminated RCTs.

Translated title of the contributionRandomized controlled trials terminated prematurely: Beneficial therapy effects
Original languageGerman
Pages (from-to)1080-1083
Number of pages4
JournalUrologe - Ausgabe A
Volume52
Issue number8
DOIs
StatePublished - Aug 1 2013

Keywords

  • Bias, epidemiological
  • Evidence-based medicine
  • Study termination, premature
  • Therapy effect

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