Radionuclide localization of lower gastrointestinal hemorrhage

G. G. Winzelberg, J. W. Froelich, K. A. McKusick, A. C. Waltman, A. J. Greenfield, C. A. Athanasoulis, H. W. Strauss

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


The authors prospectively evaluated the usefulness of abdominal radionuclide scintigraphy using 99mTc-labeled red cells as a means of monitoring for intermittent gastrointestinal bleeding over a 24-hour period in both control and actively bleeding populations. Of 32 patients with documented hemorrhage, 29 had positive scintiscans (sensitivity, 91%; 9% false negatives). Of 18 nonbleeding patients, 17 had negative scintiscans (specificity, 95%; 5% false positives). 12 of 29 patients bled from 6 to 24 hours after the study was begun. Scintiscans were positive in patients with transfusion requirements of ≥500 ml/24 hr. The authors conclude that abdominal scintigraphy with 99mTc-labeled red cells is an effective method of detecting gastrointestinal bleeding.

Original languageEnglish (US)
Pages (from-to)465-469
Number of pages5
JournalUnknown Journal
Issue number2
StatePublished - Jan 1 1981


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