Alzheimer's Disease (AD) is a progressive brain disorder that causes declined cognition and affects the patients' daily activities. It is the most common cause of dementia in people older than 65 years in America . About 6.2 million people aged 65 and older were diagnosed with Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) in the U.S. in 2021, and the number is projected to increase to 7.2 million in 2025 and to 13.8 million in 2060 . Health disparities are characterized as preventable gaps in the burden of the disease across different races, socio-economic groups, sex or other subgroups. It is noticed that the prevalence of AD/ADRD is higher among African Americans than Whites, which indicates that racial/ethnic disparity may exist in this disease -. There are no efficient treatments to prevent or reverse the progression of this disease. Unlike AD/ADRD patients, people with mild cognitive impairment (MCI), a prodromal stage of AD/ADRD, can still perform daily activities independently, which makes studies about the progression from MCI to AD/ADRD important. However, limited studies have investigated the potential existence of racial disparities from the disease progression perspective, to the best of our knowledge . This study aimed to fill this gap by evaluating the racial disparities in the progression from MCI to AD/ADRD among African Americans and Whites and examining the promising predictors of disease progression for the overall group and two racial groups separately.
|Original language||English (US)|
|Title of host publication||Proceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022|
|Publisher||Institute of Electrical and Electronics Engineers Inc.|
|Number of pages||3|
|State||Published - 2022|
|Event||10th IEEE International Conference on Healthcare Informatics, ICHI 2022 - Rochester, United States|
Duration: Jun 11 2022 → Jun 14 2022
|Name||Proceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022|
|Conference||10th IEEE International Conference on Healthcare Informatics, ICHI 2022|
|Period||6/11/22 → 6/14/22|
Bibliographical noteFunding Information:
ACKNOWLEDGMENT This project was partially supported by the National Institute on Aging 3R01AT009457-04S1 (PI: Zhang).
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