Racial Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias from the Disease Progression Perspective

Haozuo Zhao, Haitao Chu, Sicheng Zhou, Fang Yu, Xianghua Luo, Rui Zhang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Alzheimer's Disease (AD) is a progressive brain disorder that causes declined cognition and affects the patients' daily activities. It is the most common cause of dementia in people older than 65 years in America [1]. About 6.2 million people aged 65 and older were diagnosed with Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) in the U.S. in 2021, and the number is projected to increase to 7.2 million in 2025 and to 13.8 million in 2060 [1]. Health disparities are characterized as preventable gaps in the burden of the disease across different races, socio-economic groups, sex or other subgroups. It is noticed that the prevalence of AD/ADRD is higher among African Americans than Whites, which indicates that racial/ethnic disparity may exist in this disease [2]-[4]. There are no efficient treatments to prevent or reverse the progression of this disease. Unlike AD/ADRD patients, people with mild cognitive impairment (MCI), a prodromal stage of AD/ADRD, can still perform daily activities independently, which makes studies about the progression from MCI to AD/ADRD important. However, limited studies have investigated the potential existence of racial disparities from the disease progression perspective, to the best of our knowledge [5]. This study aimed to fill this gap by evaluating the racial disparities in the progression from MCI to AD/ADRD among African Americans and Whites and examining the promising predictors of disease progression for the overall group and two racial groups separately.

Original languageEnglish (US)
Title of host publicationProceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages550-552
Number of pages3
ISBN (Electronic)9781665468459
DOIs
StatePublished - 2022
Event10th IEEE International Conference on Healthcare Informatics, ICHI 2022 - Rochester, United States
Duration: Jun 11 2022Jun 14 2022

Publication series

NameProceedings - 2022 IEEE 10th International Conference on Healthcare Informatics, ICHI 2022

Conference

Conference10th IEEE International Conference on Healthcare Informatics, ICHI 2022
Country/TerritoryUnited States
CityRochester
Period6/11/226/14/22

Bibliographical note

Funding Information:
ACKNOWLEDGMENT This project was partially supported by the National Institute on Aging 3R01AT009457-04S1 (PI: Zhang).

Publisher Copyright:
© 2022 IEEE.

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