Abstract
Real-time quaking induced conversion (RT-QuIC) has become a valuable diagnostic tool for protein misfolding disorders such as Creutzfeldt–Jakob disease and Parkinson's disease. Given that the technology is relatively new, academic and industry standards for quality filtering data and high throughput analysis of results have yet to be fully established. The open source R library, quicR, was developed to provide a standardized approach to RT-QuIC data analysis. quicR provides functions, which can be easily integrated into existing R workflows, for data curation, analysis, and visualization.
| Original language | English (US) |
|---|---|
| Article number | 102247 |
| Journal | SoftwareX |
| Volume | 31 |
| DOIs | |
| State | Published - Sep 2025 |
Bibliographical note
Publisher Copyright:© 2025 The Authors
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Chronic wasting disease
- Creutzfeldt–Jakob disease
- Parkinson's disease
- RT-QuIC
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