Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy

Christopher G. Rylander, Digant P. Davé, Taner Akkin, Thomas E. Milner, Kenneth R. Diller, Ashley J. Welch

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.

Original languageEnglish (US)
Pages (from-to)1509-1511
Number of pages3
JournalOptics Letters
Volume29
Issue number13
DOIs
StatePublished - Jul 1 2004

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