Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy

Christopher G. Rylander; Digant P. Davé; Taner Akkin; Thomas E. Milner; Kenneth R. Diller; Ashley J. Welch

doi:10.1364/OL.29.001509

Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy

Christopher G. Rylander, Digant P. Davé, Taner Akkin, Thomas E. Milner, Kenneth R. Diller, Ashley J. Welch

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

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Abstract

We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.

Original language	English (US)
Pages (from-to)	1509-1511
Number of pages	3
Journal	Optics Letters
Volume	29
Issue number	13
DOIs	https://doi.org/10.1364/OL.29.001509
State	Published - Jul 1 2004

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10.1364/OL.29.001509

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title = "Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy",

abstract = "We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.",

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AU - Rylander, Christopher G.

AU - Davé, Digant P.

AU - Akkin, Taner

AU - Milner, Thomas E.

AU - Diller, Kenneth R.

AU - Welch, Ashley J.

PY - 2004/7/1

Y1 - 2004/7/1

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AB - We describe a method for en face phase-contrast imaging of cells with a fiber-based differential phase-contrast optical coherence microscopy system. Recorded en face images are quantitative phase-contrast maps of cells due to spatial variation of the refractive index and (or) thickness of various cellular components. Quantitative phase-contrast images of human epithelial cheek cells obtained with the fiber-based differential phase-contrast optical coherence microscopy system are presented.

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Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy

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