Quantitative carbon detector (QCD) for calibration-free, high-resolution characterization of complex mixtures

Saurabh Maduskar, Andrew R. Teixeira, Alex D. Paulsen, Christoph Krumm, T. J. Mountziaris, Wei Fan, Paul J. Dauenhauer

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Current research of complex chemical systems, including biomass pyrolysis, petroleum refining, and wastewater remediation requires analysis of large analyte mixtures (>100 compounds). Quantification of each carbon-containing analyte by existing methods (flame ionization detection) requires extensive identification and calibration. In this work, we describe an integrated microreactor system called the Quantitative Carbon Detector (QCD) for use with current gas chromatography techniques for calibration-free quantitation of analyte mixtures. Combined heating, catalytic combustion, methanation and gas co-reactant mixing within a single modular reactor fully converts all analytes to methane (>99.9%) within a thermodynamic operable regime. Residence time distribution of the QCD reveals negligible loss in chromatographic resolution consistent with fine separation of complex mixtures including cellulose pyrolysis products.

Original languageEnglish (US)
Pages (from-to)440-447
Number of pages8
JournalLab on a Chip
Volume15
Issue number2
DOIs
StatePublished - Jan 21 2015

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Complex Mixtures
Calibration
Carbon
Detectors
Pyrolysis
Flame Ionization
Methanation
Petroleum refining
Residence time distribution
Methane
Petroleum
Waste Water
Remediation
Thermodynamics
Cellulose
Gas chromatography
Gas Chromatography
Biomass
Heating
Ionization

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Quantitative carbon detector (QCD) for calibration-free, high-resolution characterization of complex mixtures. / Maduskar, Saurabh; Teixeira, Andrew R.; Paulsen, Alex D.; Krumm, Christoph; Mountziaris, T. J.; Fan, Wei; Dauenhauer, Paul J.

In: Lab on a Chip, Vol. 15, No. 2, 21.01.2015, p. 440-447.

Research output: Contribution to journalArticle

Maduskar S, Teixeira AR, Paulsen AD, Krumm C, Mountziaris TJ, Fan W et al. Quantitative carbon detector (QCD) for calibration-free, high-resolution characterization of complex mixtures. Lab on a Chip. 2015 Jan 21;15(2):440-447. https://doi.org/10.1039/c4lc01180e
Maduskar, Saurabh ; Teixeira, Andrew R. ; Paulsen, Alex D. ; Krumm, Christoph ; Mountziaris, T. J. ; Fan, Wei ; Dauenhauer, Paul J. / Quantitative carbon detector (QCD) for calibration-free, high-resolution characterization of complex mixtures. In: Lab on a Chip. 2015 ; Vol. 15, No. 2. pp. 440-447.
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