Quantifying the remineralization of artificial caries lesions using PS-OCT

Robert S. Jones, Daniel Fried

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations


New optical imaging methods are needed to determine whether caries lesions (tooth decay) are active and progressing or have become remineralized and arrested and are no longer progressing. The objective of this study was to use Polarization Sensitive Optical Coherence Tomography (PS-OCT) to image the fluoride enhanced remineralization of artificial enamel lesions. Artificial lesions were created by an acetate buffer on smooth enamel surfaces and were exposed for 20 days to a 2 ppm fluoride containing remineralization solution. PS-OCT images revealed the presence of a low scattering surface zone after the artificial lesions were remineralized. These samples displayed intact non-depolarizing surface zones when analyzed with Polarized Light Microscopy (PLM). No statistical difference in lesion depth before and after remineralization was found with both PS-OCT and PLM. The remineralized lesions showed a significant decrease in the overall integrated reflectivity compared with the demineralized lesions. Digital Microradiography confirmed the increase in mineral volume of the remineralized surface zone. This study determined that PS-OCT can image the restoration of the surface zone enamel after fluoride-enhanced remineralization of artificial in vitro dental caries.

Original languageEnglish (US)
Title of host publicationLasers in Dentistry XII
StatePublished - 2006
EventLasers in Dentristry XII - San Jose, CA, United States
Duration: Jan 22 2006Jan 22 2006

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceLasers in Dentristry XII
Country/TerritoryUnited States
CitySan Jose, CA


  • Dental caries
  • Polarization-sensitive optical coherence tomography
  • Remineralization


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