Quality of life appears similar between survivors of indolent and aggressive non-Hodgkin lymphoma

Anne H. Blaes, Linan Ma, Yan Zhang, Bruce A. Peterson

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Few studies have examined the quality of life (QOL) in survivors of non-Hodgkin lymphoma (NHL). A total of 109 patients with NHL (58 aggressive [AGG], 51 indolent [IND]) completed two health-related QOL assessments using the Medical Outcomes Study 36-Item Short-Form Healthy Survey (MOS SF-36) and the Functional Assessment in Cancer Therapy Fatigue (FACT-F). Scores between IND and AGG were compared using a two-sample t-test. Multiple linear regression was performed to account for any potentially explanatory variables. Overall, 70.6% had received chemotherapy and 55% had received immunotherapy. Some 17.6% of the IND group had received no therapy. The overall physical and mental component QOL scores of the SF-36 did not differ between survivors. Physical function in survivors of IND was significantly better when compared with that of AGG NHL. Our study reports a similar overall QOL between survivors of IND and AGG NHL. Physical function, however, may be more impaired in survivors of AGG NHL.

Original languageEnglish (US)
Pages (from-to)2105-2110
Number of pages6
JournalLeukemia and Lymphoma
Volume52
Issue number11
DOIs
StatePublished - Nov 2011

Keywords

  • Cancer survivorship
  • Lymphoma
  • Non-Hodgkin lymphoma
  • Quality of life

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