QSAR for the Organophosphate-Induced Inhibition and ‚Aging‚ of the Enzyme Neuropathy Target Esterase (NTE)

Keyphrases

• Aging 100%
• Organophosphate 100%
• Neuropathy Target Esterase 100%
• Acephate 80%
• Neuropathy 60%
• Organophosphorus Pesticides 60%
• Acetylcholinesterase 40%
• Coumaphos 40%
• Methamidophos 40%
• Biological Indices 20%
• Dipole Moment 20%
• Inhibition Rate 20%
• Distinct Mechanism 20%
• QSAR Model 20%
• Topological Indices 20%
• AChE Inhibitors 20%
• Cholinergic Toxicity 20%
• AChE Activity 20%
• Esterase Inhibition 20%
• Aging Index 20%
• Toxicity Potential 20%
• Hydrogen Bonds (H-bonds) 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Quantitative Structure-Activity Relationship 100%
• Neurotoxic Esterase 100%
• Organophosphate 100%
• Acephate 57%
• Acetylcholinesterase 57%
• Neuropathy 42%
• Methamidophos 28%
• Phenylphosphonothioic Acid O Ethyl O (4 Nitrophenyl) Ester 28%
• Coumaphos 28%
• Cholinergic Receptor Stimulating Agent 14%
• Esterase Inhibitor 14%

Chemistry

• Organophosphate 100%
• Acephate 57%
• EPN 28%
• Methamidophos 28%
• Coumaphos 28%
• % Inhibition 14%
• Dipole Moment 14%
• Cholinergic 14%
• Esterase Inhibitor 14%