Pyloric reflux gastritis: The offending agent

John P. Delaney, Thomas A. Broadie, Philip L. Robbins

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Tubes of canine gastric corpus were constructed so that the mucosa was exposed chronically to jejunal contents, pancreatic juice, or bile. Biopsies of these mucosae obtained 4 to 24 months later were compared with each other and with the normal stomach for parietal cell numbers, mucus cell numbers, inflammation, glandular disorder, and surface-cell hyperplasta. All three preparations showed marked gastritis, but whole jejunal contents caused more severe changes than did either pancreatic juice or bile, which were approximately equal.

Original languageEnglish (US)
Pages (from-to)764-772
Number of pages9
JournalSurgery
Volume77
Issue number6
StatePublished - Jun 1975

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