Two cases of paroxysmal atrial fibrillation (AF) first occurred 15 and 36 years, respectively, after isolated direct suture closure of an atrial septal defect (ASD) and failed to be controlled by antiarrhythmic drug therapy. In these cases, an atrial transseptal procedure was feasible and no residual iatrogenic ASD was observed, even after multiple procedures. Pulmonary vein (PV) isolation was also feasible and safe and could eliminate the AF completely. PV isolation may become an alternative to antiarrhythmic drug therapy in patients with paroxysmal AF occurring late after an isolated direct suture closure of an ASD.
- Atrial fibrillation
- Atrial septal defect
- Pulmonary vein isolation
- Radiofrequency catheter ablation