Pulmonary hypertension in systemic lupus erythematosus: Effect of vasodilators on pulmonary hemodynamics

Maren L Mahowald, E. K. Weir, D. J. Ridley, R. P. Messner

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Hemodynamic studies of the response of the pulmonary vasculature to vasodilator drugs were performed in 3 patients with systemic lupus and pulmonary hypertension. In one patient isoproterenol infusion produced a reduction in total pulmonary resistance, but increased pulmonary blood flow and pulmonary artery pressure. No significant change in pulmonary artery pressure or resistance was noted with nifedipine in any of the patients. One woman with associated pulmonary infiltrates improved symptomatically with high dose steroids.

Original languageEnglish (US)
Pages (from-to)773-777
Number of pages5
JournalJournal of Rheumatology
Volume12
Issue number4
StatePublished - Jan 1 1985

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