TY - JOUR
T1 - Pulmonary disease in HIV-infected adults in the era of antiretroviral therapy
AU - Fitzpatrick, Meghan E.
AU - Kunisaki, Ken M.
AU - Morris, Alison
N1 - Publisher Copyright:
© Copyright 2018 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2018/1/28
Y1 - 2018/1/28
N2 - HIV in the antiretroviral therapy era is characterized by multimorbidity and the frequent occurrence of HIV-associated non-AIDS chronic health conditions. Respiratory symptoms and chronic pulmonary diseases, including chronic obstructive pulmonary disease, asthma, and cardiopulmonary dysfunction, are among the conditions that may present in persons living with HIV. Tobacco smoking, which is disproportionately high among persons living HIV, strongly contributes to the risk of pulmonary disease. Additionally, features associated with and at times unique to HIV, including persistent inflammation, immune cell activation, oxidative stress, and dysbiosis, may also contribute. This review summarizes the available literature regarding epidemiology of and risk factors for respiratory symptoms and chronic pulmonary disease in the current era.
AB - HIV in the antiretroviral therapy era is characterized by multimorbidity and the frequent occurrence of HIV-associated non-AIDS chronic health conditions. Respiratory symptoms and chronic pulmonary diseases, including chronic obstructive pulmonary disease, asthma, and cardiopulmonary dysfunction, are among the conditions that may present in persons living with HIV. Tobacco smoking, which is disproportionately high among persons living HIV, strongly contributes to the risk of pulmonary disease. Additionally, features associated with and at times unique to HIV, including persistent inflammation, immune cell activation, oxidative stress, and dysbiosis, may also contribute. This review summarizes the available literature regarding epidemiology of and risk factors for respiratory symptoms and chronic pulmonary disease in the current era.
KW - HIV
KW - asthma
KW - chronic obstructive
KW - hypertension
KW - pulmonary
KW - pulmonary disease
KW - ventricular dysfunction
UR - http://www.scopus.com/inward/record.url?scp=85041462254&partnerID=8YFLogxK
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U2 - 10.1097/QAD.0000000000001712
DO - 10.1097/QAD.0000000000001712
M3 - Review article
C2 - 29194119
AN - SCOPUS:85041462254
VL - 32
SP - 277
EP - 292
JO - AIDS
JF - AIDS
SN - 0269-9370
IS - 3
ER -