Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary

Robert F. Tamburro; Kenneth R. Cooke; Stella M. Davies; Samuel Goldfarb; James S. Hagood; Ashok Srinivasan; Marie E. Steiner; Dennis Stokes; Nancy DiFronzo; Nahed El-Kassar; Nonniekaye Shelburne; Aruna Natarajan

doi:10.1513/annalsats.202001-006ot

Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary

Robert F. Tamburro, Kenneth R. Cooke, Stella M. Davies, Samuel Goldfarb, James S. Hagood, Ashok Srinivasan, Marie E. Steiner, Dennis Stokes, Nancy DiFronzo, Nahed El-Kassar, Nonniekaye Shelburne, Aruna Natarajan

Pediatric Hematology/Oncology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Approximately 2,500 pediatric hematopoietic cell transplants (HCTs), most of which are allogeneic, are performed annually in the United States for life-threatening malignant and nonmalignant conditions. Although HCT is undertaken with curative intent, post-HCT complications limit successful outcomes, with pulmonary dysfunction representing the leading cause of nonrelapse mortality. To better understand, predict, prevent, and/or treat pulmonary complications after HCT, a multidisciplinary group of 33 experts met in a 2-day National Institutes of Health Workshop to identify knowledge gaps and research strategies most likely to improve outcomes. This summary of Workshop deliberations outlines the consensus focus areas for future research.

Original language	English (US)
Pages (from-to)	381-394
Number of pages	14
Journal	Annals of the American Thoracic Society
Volume	18
Issue number	3
DOIs	https://doi.org/10.1513/annalsats.202001-006ot
State	Published - Mar 1 2021

Bibliographical note

Funding Information:
Supported by the National Heart, Lung, Blood Institute, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the National Cancer Institute, U.S. National Institutes of Health.

Publisher Copyright:
Copyright © 2021 by the American Thoracic Society

Keywords

Acute respiratory distress syndrome
Hematopoietic cell transplantation
Pediatrics
Pulmonary complications
Respiratory failure

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10.1513/annalsats.202001-006ot

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Tamburro, R. F., Cooke, K. R., Davies, S. M., Goldfarb, S., Hagood, J. S., Srinivasan, A., Steiner, M. E., Stokes, D., DiFronzo, N., El-Kassar, N., Shelburne, N., & Natarajan, A. (2021). Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary. Annals of the American Thoracic Society, 18(3), 381-394. https://doi.org/10.1513/annalsats.202001-006ot

Tamburro, RF, Cooke, KR, Davies, SM, Goldfarb, S, Hagood, JS, Srinivasan, A, Steiner, ME, Stokes, D, DiFronzo, N, El-Kassar, N, Shelburne, N & Natarajan, A 2021, 'Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary', Annals of the American Thoracic Society, vol. 18, no. 3, pp. 381-394. https://doi.org/10.1513/annalsats.202001-006ot

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Pulmonary Complications of Pediatric Hematopoietic Cell Transplantation A National Institutes of Health Workshop Summary

Abstract

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