Pulmonary blastoma with renal metastasis responds to sorafenib

Keerthi Mulamalla, Alexander M. Truskinovsky, Arkadiusz Z Dudek

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Biphasic pulmonary blastoma is a rare malignancy of the lung composed of proliferating epithelial and mesenchymal cells with a high vessel density at the tumor periphery. We report a rare case of renal metastasis of biphasic pulmonary blastoma that responded to sorafenib, an oral multikinase inhibitor. After 2 months of treatment with sorafenib, the renal tumor size decreased sufficiently to allow a safe laparoscopic radical nephrectomy. We believe that further studies are warranted to confirm the possible effects of sorafenib on pulmonary blastomas.

Original languageEnglish (US)
Pages (from-to)344-347
Number of pages4
JournalJournal of Thoracic Oncology
Issue number4
StatePublished - Apr 2007


  • Biphasic pulmonary blastoma
  • Sorafenib


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