Pulmonary arterial hypertension

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Pulmonary arterial hypertension (PAH) is a debilitating disease characterized by progressive adverse remodeling of the resistance pulmonary arteries, ultimately leading to right ventricular (RV) failure and death. It is defined by increases in pulmonary arterial pressures (PAP), pulmonary vascular resistance (PVR), and ultimately, right ventricular failure. The field of PAH has made remarkable progress in the last two decades with understanding in the pathogenesis and improvements in therapeutic and prognostic tools. In this chapter, we will review the definition, pathogenesis, epidemiology, clinical presentation, management, and prognostication of PAH in the current era.

Original languageEnglish (US)
Title of host publicationArterial Disorders
Subtitle of host publicationDefinition, Clinical Manifestations, Mechanisms and Therapeutic Approaches
PublisherSpringer International Publishing
Pages313-332
Number of pages20
ISBN (Electronic)9783319145563
ISBN (Print)9783319145556
DOIs
StatePublished - Jan 1 2015

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