Adenocarcinoma pulmonar em um bovino

Translated title of the contribution: Pulmonary adenocarcinoma in a bovine

Aline de Marco Viott, Ingeborg Maria Langohr, Fábio Augusto Vannucci, Aliny Pontes Almeida, Rômulo Cerqueira Leite, Roselene Ecco

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

An adult Guzera cow, dysplaying for two weeks signs of right-sided congestive heart failure died during the transport to the veterinary hospital. At necropsy, the left cranial lung lobe was moderately increased in volume and firm. The parenchyma of the affected lung lobe was white and contained multiple 0.3 to 1.5cm in diameter, yellow, dry, friable nodules. Similar changes were observed in bronchial and mediastinal lymph nodes, parietal pericardium, epicardium, and adventitia of the pulmonary artery. Microscopically, the pulmonary tissue mass was composed of neoplastic epithelial cells arranged in acini lined by two or more layers, some with intraluminal papillary projections. Anisokaryosis was marked, and mitotic index was moderate (2-3 mitosis in high field). Abundant fibrous connective tissue surrounded the neoplastic cell aggregates. Foci of necrosis and mineralization were moderate. Similar microscopic changes were observed in bronchial and mediastinal lymph nodes, visceral and parietal pericardium and adventitia of the pulmonary artery. With liver chronic generalized congestion exception, no other macro or microscopic lesions were observed. Microscopic findings were consistent with pulmonary adenocarcinoma with regional metastases. The right-sided congestive heart failure was probably due to obstruction of lymphatic drainage by metastases.

Translated title of the contributionPulmonary adenocarcinoma in a bovine
Original languagePortuguese
Pages (from-to)484-487
Number of pages4
JournalCiencia Rural
Volume40
Issue number2
StatePublished - Feb 1 2010

Keywords

  • Bovine
  • Metastases
  • Pulmonary adenocarcinoma
  • Right congestive heart failure

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