A unique partnership has been established between researchers at Iowa State University and the American Lung Association of Iowa. This partnership has resulted in the statewide application of an effective clinic method for smoking cessation.From a very modest beginning (four public service clinics were held in the 1979-1980 fiscal year) the program has evolved to a total of 103 clinics in the 1987-1988 fiscal year. The public service clinics are continually revised to reflect current laboratory findings. Long-term follow-up data are routinely collected on all clinic participants. Costs are kept at relatively modest levels through use of lay facilitators and donated clinic sites. Quality control and evaluation are systematically maintained. One-year abstinence levels have averaged 33%. The clinics are now continuing under the auspices of the American Lung Association of Iowa. This model of laboratory research combined with field application should be replicable in other locations and with additional types of public health problems.