Abstract
Chimeric antigen receptor T-cells and other immunotherapies have markedly changed the paradigm of treatment for patients with relapsed or refractory hematologic malignancies. While notable in efficacy, immunotherapy is characterized by a significant possibility of life-threatening side effects. Consequently, patients are often required to have informal family caregivers present and to stay near the treating center for several weeks after cell infusion. Further, the responsibility of managing a great deal of physical care and emotional support falls to these caregivers. Given the novelty of immunotherapy treatment, there is a need to better understand the psychosocial experience of patients receiving this treatment and their caregivers. This article describes the psychosocial characteristics of patients undergoing cellular immunotherapies and their caregivers across time, including patient/caregiver distress, coping, and caregiver burden and preparedness.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 364-370 |
| Number of pages | 7 |
| Journal | Leukemia and Lymphoma |
| Volume | 64 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2023 |
Bibliographical note
Funding Information:This work was supported by the ECOG-ACRIN under Grant 5UG1CA189828-07; Federal Award Identification Number: UG1CA189828. We would like to thank the patients, caregivers, and medical teams for helping us with this study. Editorial assistance was provided by the Moffitt Cancer Center’s Office of Scientific Publishing by Daley Drucker and Gerard Hebert; no compensation was given beyond their regular salaries.
Publisher Copyright:
© 2022 Informa UK Limited, trading as Taylor & Francis Group.
Keywords
- CAR-T
- cancer
- caregiver
- cellular immunotherapy
- psychosocial
PubMed: MeSH publication types
- Journal Article
- Research Support, N.I.H., Extramural
