Psychometric properties of WHOQOL-BREF-THAI in patients with HIV/AIDS

Phantipa Sakthong, Jon C Schommer, Cynthia R. Gross, Rungpetch Sakulbumrungsil, Wisit Prasithsirikul

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


Objective: To assess reliability and validity of the Thai abbreviated version of World Health Organization quality of life (WHOQOL-BREF-THAI) in HIV/AIDS patients. Material and Method: The present study is descriptive research. Data were purposively collected from 120 HIV/AIDS outpatients at Bamrasnaradura Infectious Disease Institute, Thailand, during September-December, 2004. Results: Cronbach's alpha ranged from 0.61 to 0.81 across domains. Exploratory factor analysis identified four major domains: physical, psychological, social and environmental domains, corresponding to the four WHOQOL-BREF domains. The four domain scores correlated positively with general health satisfaction and overall quality of life questions (all p < 0.01 except general health & social domain p < 0.05), and correlated negatively with the frequency and severity of HIV symptoms (all p < 0.01). The four domain scores discriminated between patients with higher and lower frequency and severity of HIV symptoms (all p < 0.01). Conclusion: The present study shows that WHOQOL-BREF THAI can be a good generic health-related quality of life instrument in HIV/AIDS patients.

Original languageEnglish (US)
Pages (from-to)2449-2460
Number of pages12
JournalJournal of the Medical Association of Thailand
Issue number11
StatePublished - Nov 2007

Bibliographical note

Copyright 2008 Elsevier B.V., All rights reserved.


  • Health-related quality of life
  • Reliability
  • Validity


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